Genomic structure and diversity of Plasmodium falciparum in Southeast Asia reveal recent parasite migration patterns
oleh: Amol C. Shetty, Christopher G. Jacob, Fang Huang, Yao Li, Sonia Agrawal, David L. Saunders, Chanthap Lon, Mark M. Fukuda, Pascal Ringwald, Elizabeth A. Ashley, Kay Thwe Han, Tin Maung Hlaing, Myaing M. Nyunt, Joana C. Silva, Kathleen E. Stewart, Christopher V. Plowe, Timothy D. O’Connor, Shannon Takala-Harrison, Artemisinin Resistance Confirmation, Characterization, and Containment (ARC3), Artemisinin Resistance Containment and Elimination (ARCE), Tracking Resistance to Artemisinin Collaboration (TRAC)
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2019-06-01 |
Deskripsi
Understanding genomic variation in Plasmodium falciparum parasites and inferring migration patterns can guide malaria elimination strategies. Using genome-wide data for 1722 parasites collected from 54 districts, the authors use identity-by-descent approaches to estimate regional parasite migration and spread of artemisinin drug resistance.