Find in Library

Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is associated with <em>Helicobacter pylori</em> infection. <em>H. pylori</em> eradication can be performed as a primary therapy regardless of H. pylori status. In Korea, six articles were published about low-grade gastric MALT lymphoma with H. pylori. Complete regression rate after <em>H. pylori</em> eradication is reported at 74.5% to 94.4%. Radiotherapy results in favorable clinical long-term outcomes in patients with early-stage gastric MALT lymphoma who fail <em>H. pylori</em> eradication therapy and those who are H. pylori negative. Chemotherapy could be reserved for patients with metastatic or high-grade lymphoma. In gastric MALT lymphoma, patients with polypoid type on initial endoscopy had a higher likelihood of recurrence than those with diffuse infiltration or ulceration types. The depth of invasion, location of lesions, and chromosomal abnormality with t(11;18) together are predictive factors for failure to remission by <em>H. pylori</em> eradication. (Korean J Gastroenterol 2016;68:175-178)