Aschoff’s rule on circadian rhythms orchestrated by blue light sensor CRY2 and clock component PRR9

oleh: Yuqing He, Yingjun Yu, Xiling Wang, Yumei Qin, Chen Su, Lei Wang

Format: Article
Diterbitkan: Nature Portfolio 2022-10-01

Deskripsi

Circadian pace is modulated by light intensity. Here the authors show that CRY2 interacts with PRR9 to mediate blue light input to the circadian clock and is degraded at higher light intensity offering a mechanistic explanation as to how intensity can modify clock place.