Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy Controls
oleh: Jacob N Ablin, Natalia Aronov, Ilan Shimon, Hannah Kanety, Clara Pariente, Valerie Aloush, Ori Elkayam, David Levartovsky
| Format: | Article |
|---|---|
| Diterbitkan: | Wiley 2012-01-01 |
Deskripsi
BACKGROUND: Leptin, an adipocyte-produced cytokine, interacts with various hormones, including those of the hypothalamic-pituitary-adrenal axis. Fibromyalgia is a syndrome characterized by widespread pain accompanied by tenderness. The pathogenesis involves a disturbance in pain processing and transmission by the central nervous system, leading to a general increase in pain perception.