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<p><strong>Background: </strong>Cutaneous and subcutaneous metastasis from an underlying primary, indicates a dismal outcome for patients. It is appropriate to use fine needle aspiration cytology as a minimally invasive method for diagnosis. This study emphasises the role of fine needle aspiration cytology in diagnosing metastatic skin nodules.</p> <p><strong>Materials and methods: </strong>This was a retrospective study in which the record of all patients subjected to fine needle aspiration cytology from April 2008 &ndash; Nov 2010 in the Department of Pathology, Tribhuvan University Teaching Hospital, were reviewed. Of 5,927 patients, 19 cases diagnosed as metastatic skin lesions were included in the study.</p> <p><strong>Results: </strong>Out of 19 patients with metastatic skin nodules, 9 patients had metastasis simultaneously with the primary and 8 cases were previously diagnosed. All metastases were from internal solid organ tumours with male to female ratio of 1.7:1. Lung carcinoma was the most common to metastasis in both sexes which included adenocarcinoma (5 cases) and squamous cell carcinoma (6 cases). Common sites for cutaneous/subcutaneous metastasis were the chest wall (9 cases) followed by abdomen (4 cases) and scalp (3 cases).</p> <p><strong>Conclusion: </strong>Fine needle aspiration cytology can diagnose a variety of skin lesions which may be supportive in diagnosing a metastasis in cases with known primaries or it may offer a clue to underlying malignancy in unsuspected cases.<strong> </strong></p> <p><strong>Keywords: </strong>Fine needle aspiration; Cutaneous metastases</p> <p>DOI: 10.3126/jpn.v1i1.4449</p> <p><em>Journal of Pathology of Nepal </em>(2011) Vol.1, 37-40 &nbsp;</p>