Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells
oleh: Lee M. Butcher, Mitsuteru Ito, Minodora Brimpari, Tiffany J. Morris, Filipa A. C. Soares, Lars Ährlund-Richter, Nessa Carey, Ludovic Vallier, Anne C. Ferguson-Smith, Stephan Beck
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-01-01 |
Deskripsi
The methylation of non-CpG residues is a poorly understood marker of pluripotent cells, gradually lost as cells differentiate. Here the authors show non-CG methylation can be used as a marker of differentiation potential.