Disulfide-compatible phage-assisted continuous evolution in the periplasmic space
oleh: Mary S. Morrison, Tina Wang, Aditya Raguram, Colin Hemez, David R. Liu
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-10-01 |
Deskripsi
The directed evolution of antibodies yields important tools for research and therapy. Here the authors develop a periplasmic phage-assisted continuous evolution platform for improvement of protein-protein interactions in the disulfidecompatible E. coli periplasm.