Sudden Cardiac Arrest in a Patient With Mitral Valve Prolapse and LMNA and SCN5A Mutations
oleh: Asha M. Mahajan, MD, Yuval Itan, PhD, Marina Cerrone, MD, James Horowitz, MD, Linda Borneman, MA, Larry Chinitz, MD, Lior Jankelson, MD, PhD
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2021-02-01 |
Deskripsi
Bileaflet mitral valve prolapse (Bi-MVP) is associated with increased risk for cardiac arrest. We describe a patient who presented after a cardiac arrest with Bi-MVP and variants in Lamin A/C (LMNA) and the sodium channel alpha-subunit 5a (SCN5A). Genetic variants may be the culprit for arrhythmogenesis in Bi-MVP patients. (Level of Difficulty: Intermediate.)