N-[(2S)-4-Chloro-2-(l-menthyloxy)-5-oxo-2,5-dihydrofuran-3-yl]-l-valine
oleh: Xiu-Mei Song, Zhao-Yang Li, Zhao-Yang Wang, Jian-Xiao Li
| Format: | Article |
|---|---|
| Diterbitkan: | International Union of Crystallography 2009-07-01 |
Deskripsi
The title compound, C19H30ClNO5, was obtained by the tandem asymmetric Michael addition–elimination reaction of (5S)-3,4-dichloro-5-(l-menthyloxy)furan-2(5H)-one and l-valine in the presence of potassium hydroxide. The furanone unit is approximately planar (r.m.s. deviation = 0.0204 Å) and the six-membered cyclohexane ring adopts a chair conformation. The crystal structure is stabilized by a network of O—H...O and N—H...O hydrogen bonds.