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Mitochondrial network configuration influences sarcomere and myosin filament structure in striated muscles
oleh: Prasanna Katti, Alexander S. Hall, Hailey A. Parry, Peter T. Ajayi, Yuho Kim, T. Bradley Willingham, Christopher K. E. Bleck, Han Wen, Brian Glancy
Format: | Article |
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Diterbitkan: | Nature Portfolio 2022-10-01 |
Deskripsi
How different physical configurations between sarcomeres and mitochondria alter energetic support for contractile function of skeletal muscle is not clear. Here the authors use advanced 3D imaging and analysis techniques to show how space is made for mitochondria within the tightly packed sarcomere networks of striated muscle cells.