Mathematical analysis of an HBV model with antibody and spatial heterogeneity

oleh: Kuo-Sheng Huang, Yu-Chiau Shyu, Chih-Lang Lin, Feng-Bin Wang

Format: Article
Diterbitkan: AIMS Press 2020-01-01

Deskripsi

In this paper, we modify the HBV model proposed in [1] to include the spatial variations of free antibody, virus-antibody complexes, and free virus. By using comparison arguments and theory of uniform persistence, we can show that the persistene/extinction of HBV can be determined by the reproduction number(s).