Multi-level and lineage-specific interactomes of the Hox transcription factor Ubx contribute to its functional specificity

oleh: Julie Carnesecchi, Gianluca Sigismondo, Katrin Domsch, Clara Eva Paula Baader, Mahmoud-Reza Rafiee, Jeroen Krijgsveld, Ingrid Lohmann

Format: Article
Diterbitkan: Nature Portfolio 2020-03-01

Deskripsi

Many transcription factors regulate gene expression in a lineage- and process-specific manner, despite being expressed in several cell types. Here, the authors show that the Hox transcription factor Ubx has lineage-specific interactomes, which contribute to its cell context-dependent functions.