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Abietane Diterpenoids Isolated from <i>Clerodendrum bracteatum</i> and Their Antioxidant and Cytotoxic Activities
oleh: Pingting Li, Lingling Li, Qin Zhu, Mingfeng Xu
Format: | Article |
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Diterbitkan: | MDPI AG 2021-08-01 |
Deskripsi
Two new abietane diterpenoids (<b>1,2</b>), along with five known diterpenoids (<b>3</b>–<b>7</b>), were first isolated and purified from the stems of <i>Clerodendrum bracteatum</i>. The structures of the new compounds were established by extensive analysis of mass spectrometric and 1-D, 2-D NMR spectroscopic data. Their antioxidant activities were determined on DPPH radical scavenging and ABTS. The in vitro cytotoxic activities of the compounds were evaluated against the HL-60 and A549 cell lines by the MTT method.