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<b>AIM:</b>To assess patients’ visual performance with glistenings in one piece soft hydrophobic acrylic intraocular lenses (IOLs) (Alcon) 2 years postoperatively.<b>METHODS:</b>This cross section trial included 120 eyes with one piece IOL at 2 years postoperatively. Glistening was classified in 4 groups, ranging from 0 (none) to 3 (most evident) according to their severity in IOLs optics observed under a slit lamp. All eyes underwent a uncorrected and best-corrected visual acuity evaluation (UCVA and BCVA, LogMAR scale), a complete clinical examination, a contrast sensitivity (CS) evaluation by F.A.C.T chart, and a visual field test by Humphrey Field AnalyzerⅡ(HFA). One-way ANOVA was used for quantitative data, while Pearson <i>χ</i>² test was used for qualitative data to analyze the visual function of 4 glistening groups.<b>RESULTS:</b> Totally 120 eyes were enrolled with 30 eyes in each glistening group. There was no statistical correlation between glistening grades and patients’ age, IOLs power, postoperative UCVA and BCVA (<i>P</i>&gt;0.05). Quantificationally, CS values among each group were not statistically different. However, qualitative analysis showed there were more eyes in grade 3 group than in grade 0 group having abnormally declined CS at high spatial frequency (10% <i>vs</i> 36.7% at 18 cpd, <i>P=</i>0.029; 6.7% <i>vs</i> 26.7% at 12 cpd, <i>P</i>=0.013). Mean deviation (MD) of the visual field test was -2.14±2.31, -1.97±2.23, -3.02±3.17, -4.12±3.38 in group 0 to 3 respectively. There was a significant decrease in the most serious glistenings group (<i>P</i> =0.018).<b>CONCLUSION:</b>Glistenings may potentially have an impact on contrast sensitivity at high spatial frequencyand MD in visual field test.