SMAD2/3 mediate oncogenic effects of TGF-β in the absence of SMAD4

oleh: Adrien Bertrand-Chapel, Cassandre Caligaris, Tanguy Fenouil, Clara Savary, Sophie Aires, Sylvie Martel, Paul Huchedé, Christelle Chassot, Véronique Chauvet, Victoire Cardot-Ruffino, Anne-Pierre Morel, Fabien Subtil, Kayvan Mohkam, Jean-Yves Mabrut, Laurie Tonon, Alain Viari, Philippe Cassier, Valérie Hervieu, Marie Castets, Alain Mauviel, Stéphanie Sentis, Laurent Bartholin

Format: Article
Diterbitkan: Nature Portfolio 2022-10-01

Deskripsi

In pancreatic ductal adenocarcinoma cells and patient tissue, SMAD2/3 is shown to mediate oncogenic effects of TGF-β in the absence of SMAD4.