The contribution of common and rare genetic variants to variation in metabolic traits in 288,137 East Asians

oleh: Young Jin Kim, Sanghoon Moon, Mi Yeong Hwang, Sohee Han, Hye-Mi Jang, Jinhwa Kong, Dong Mun Shin, Kyungheon Yoon, Sung Min Kim, Jong-Eun Lee, Anubha Mahajan, Hyun-Young Park, Mark I. McCarthy, Yoon Shin Cho, Bong-Jo Kim

Format: Article
Diterbitkan: Nature Portfolio 2022-11-01

Deskripsi

Metabolic traits are heritable intermediate phenotypes widely used in assessing the risk of various diseases. By conducting a genome-wide meta-analysis for metabolic traits in 288,137 East Asians, the authors highlight the interplay of common and rare variants on inherited risk of metabolic traits.