β-actin dependent chromatin remodeling mediates compartment level changes in 3D genome architecture
oleh: Syed Raza Mahmood, Xin Xie, Nadine Hosny El Said, Tomas Venit, Kristin C. Gunsalus, Piergiorgio Percipalle
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-09-01 |
Deskripsi
β-actin loss can affect gene expression and heterochromatin organization. Here the authors conduct a comprehensive genomic analysis of β-actin knockout mouse embryonic fibroblasts (MEFs) to investigate the impact of changes in β-actin levels on 3d genome architecture and chromatin remodeling activities of BAF and polycomb proteins.