Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2
oleh: Alicia S. Wilson, Katrina L. Randall, Jessica A. Pettitt, Julia I. Ellyard, Antje Blumenthal, Anselm Enders, Benjamin J. Quah, Tobias Bopp, Christopher R. Parish, Anne Brüstle
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-01-01 |
Deskripsi
Neutrophils are critical in the immune response to infective agents and have multiple effector strategies including the production of extracellular traps termed NETs. Here the authors show a link between NET production and Th17 differentiation which mechanistically occurs downstream of TLR2 signalling.