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Phytochemical analysis showed that Leontice leontopetalum contained many quinolizidine alkaloids, tannins, phenolic,  flavonoids  and many other bioactive contents. The pharmacological studies revealed  that Leontice leontopetalum possessed antioxidant, antidiabetic, convulsant and anti convulsant, cytotoxic, anticholinesterase cardiovascular and smooth muscle contractile effects. The current mini review discussed the chemical constituents and pharmacological effects of Leontice leontopetalum.