Implications in dental treatment during the use of antiresorptive drugs - a literature review

oleh: Aleksandra Dziewulska, Weronika Kiełt, Julia Kozłowska, Gabriela Broniec, Barbara Wajdowicz, Aleksandra Kudła, Rozalia Czapiewska, Aleksandra Wróbel, Laura Pacek, Klaudia Kowalska

Format: Article
Diterbitkan: Kazimierz Wielki University 2024-10-01

Deskripsi

Introduction: Antiresorptive drugs such as bisphosphonates and denosumab are crucial for treating osteoporosis, metastatic bone disease, and hypercalcemia by inhibiting osteoclast function. They can lead to medication-related osteonecrosis of the jaw (MRONJ) following invasive dental procedures, requiring careful management to mitigate potential adverse effects.   Purpose of work: Synthesis of knowledge about the impact of taking antiresorptive drugs on aspects of dental treatment.   Materials and methods: Materials used in this study were found in the PubMed and Google Scholar database, using the following key words “antiresorptives”, “bisphosphonates”, “dental treatment”, “osteonecrosis of the jaw”  Summary: Antiresorptive drugs like bisphosphonates and denosumab are essential for managing osteoporosis and other bone diseases but pose challenges in dental care, notably with risks such as medication-related osteonecrosis of the jaw (MRONJ). These medications influence treatment strategies across orthodontics, implantology, periodontal therapy, and endodontics, necessitating careful management to balance therapeutic benefits with potential dental complications.