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Here we present a 79-year old man with chronic hypersensitivity pneumonitis probably caused by fungal contamination of a bagpipe. Several samples were taken from the patient's bagpipe. Four potential fungal antigens (Exophiala phaeomuriformis, Kwoniella europaea, Pyrenochaeta unguis-hominis and Aureobasidium melanogenum) as potential trigger of hypersensitivity pneumonitis were identified. A serum ELISA test with Exophiala phaeomuriformis indicated reactivity.Cessation of playing the bagpipe and application of glucocorticoids lead to an improvement of the patient's symptoms. Keywords: Hypersensitivity pneumonitis, Bagpipe, Fungal antigens, Serological testing