Genetic associations with carotid intima-media thickness link to atherosclerosis with sex-specific effects in sub-Saharan Africans
oleh: Palwende Romuald Boua, Jean-Tristan Brandenburg, Ananyo Choudhury, Hermann Sorgho, Engelbert A. Nonterah, Godfred Agongo, Gershim Asiki, Lisa Micklesfield, Solomon Choma, Francesc Xavier Gómez-Olivé, Scott Hazelhurst, Halidou Tinto, Nigel J. Crowther, Christopher G. Mathew, Michèle Ramsay, AWI-Gen Study, the H3Africa Consortium
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2022-02-01 |
Deskripsi
Genetic studies of disease-relevant traits have mostly been performed on European populations. Here, the authors perform a genome-wide association study for carotid intima-media thickness, in sub-Saharan African samples, finding population-specific and sex-specific loci.