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Malignant growth is the most dangerous illness with the most elevated mortality rate. Early identification of malignant growth can be fundamental in effective treatment. One of the most promising early symptomatic tools for tracking infection spread and subsequent disease treatment is biomarker-based malignant growth screening. Prostate cancer (PCa) is the most widely recognized reason for death in men and is the following driving reason for death from the disease worldwide. Prostate-specific antigen (PSA) is a fundamental biomarker for diagnosing PCa. Despite signs against its utilization in massive populace tests, PSA concentrates most on PCa biomarkers. This biomarker does remain an essential determinant in the therapy of prostate malignant growth due to its different structures and its inclusion in rehashed plans with other biomarkers. This paper depicts the most recent advances in electrochemical biosensors intended to identify different malignant growth biomarkers utilizing further sign transmission and biological detection strategies. In treating malignant prostate growth, disclosing its specific structures and inclusion in revised schemes with other biomarkers are crucial indicators.