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Introduction: Pulmonary hypertension is a progressive disease where endothelial dysfunction plays an important role in its etiology. Statins have been considered a therapeutic option for pulmonary hypertension due to their pleiotropic effects. Materials and Methods: We investigated the association between statin use and echocardiographic parameters in 73 patients with pulmonary hypertension (23 patients were on statin and 50 patients were not taking statin). Results: Our study showed no association between statin use and different echocardiographic parameters used to evaluation pulmonary hypertension though there was a trend toward less right ventricular dilatation favoring the statin group (25.20 ± 14.7 mm vs. 29.7 ± 9.5) with a P = 0.052. Conclusion: We observed noassociation between statin use and echocardiographic findings in patients with pulmonary hypertension. A larger scale studies are need to confirm our findings.