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Seasonality effects on the mineral profile of goats were evaluated. Fifty males were divided into two groups, one with mineral supplementation and one control. Seasonal evaluation was conducted during four periods: beginning, middle, and end of the dry period and middle of the rainy period. Rib and liver biopsies were performed, and blood was collected at each period to evaluate mineral accumulation. Ca, P, Cu, Fe, Mo, Zn, and Co concentrations were determined using inductively coupled plasma optical emission spectrometry after acid digestion. Normal Ca, P, and Mo; low Cu, Zn, and Co; and high Fe levels were observed in the diet. The young animals analyzed showed normal serum and bone Ca and P concentrations, suggesting no need for supplementation throughout the entire year under the conditions of this study. Iron showed high values throughout the year, being potentially dangerous especially owing to its antagonistic relationship with other elements. Cu and Zn deficiency in the diet was observed under the conditions of this study, requiring supplementation with values higher than those contained in the mineral supplement used in the middle and end of the dry period. The supply of specific mineral supplement formulated for animals farmed in the semiarid region is suggested and would reduce costs.