Gata6+ resident peritoneal macrophages promote the growth of liver metastasis
oleh: Mokarram Hossain, Raymond Shim, Woo-Yong Lee, Arlene H. Sharpe, Paul Kubes
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-07-01 |
Deskripsi
GLPMs represent a population of fetal liver derived large peritoneal cavity Gata6+ macrophages, with the capacity to invade the tissues they surround. Here, in experimental colon cancer liver metastasis models, the authors show that GLPMs invade liver metastasis directly from the peritoneum, promoting liver metastases growth.