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The objective of the study is to reveal the seasonal variations in the Hindon River water pollution with respect to chromium contamination.  The study was carried out from December 2014 to January 2017 by selecting twelve sampling stations of River Hindon. To get the extend of trace and ultratrace chromium contamination, water samples were collected from twelve different sites along the course of the River and its tributaries for summer and winter seasons. Higher concentrations of chromium (0.096mg/L) in summer and (0.088) in winter at Mohannagar (Ghaziabad) were recorded, thus indicating very high pollution of chromium at this sampling station. The concentration of chromium was determined using Atomic Absorption Spectrophotometer (AAS). In the past decades the increased use of chromium in several anthropogenic activities and consequent contamination of soil and water have become an increasing concern. Cr exists in several oxidation states but the most stable and common forms are Cr(0), Cr(III) and Cr(VI) species. Cr (VI) is a notorious environmental pollutant because it is a strong oxidant and much more toxic than Cr (III) and also carcinogenic.