Magnetic Resonance Imaging–Based Delineation of Organs at Risk in the Head and Neck Region
oleh: Viktor R. Paczona, MD, Marta E. Capala, MD, PhD, Borbála Deák-Karancsi, MD, Emőke Borzási, MD, Zsófia Együd, MD, Zoltán Végváry, MD, Gyöngyi Kelemen, MD, PhD, Renáta Kószó, MD, PhD, László Ruskó, PhD, Lehel Ferenczi, MScEng, Gerda M. Verduijn, MD, Steven F. Petit, PhD, Judit Oláh, MD, PhD, DSC, Adrienne Cserháti, MD, Florian Wiesinger, PhD, Katalin Hideghéty, MD, PhD
| Format: | Article |
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| Diterbitkan: | Elsevier 2023-03-01 |
Deskripsi
Purpose: The aim of this article is to establish a comprehensive contouring guideline for treatment planning using only magnetic resonance images through an up-to-date set of organs at risk (OARs), recommended organ boundaries, and relevant suggestions for the magnetic resonance imaging (MRI)–based delineation of OARs in the head and neck (H&N) region. Methods and Materials: After a detailed review of the literature, MRI data were collected from the H&N region of healthy volunteers. OARs were delineated in the axial, coronal, and sagittal planes on T2-weighted sequences. Every contour defined was revised by 4 radiation oncologists and subsequently by 2 independent senior experts (H&N radiation oncologist and radiologist). After revision, the final structures were presented to the consortium partners. Results: A definitive consensus was reached after multi-institutional review. On that basis, we provided a detailed anatomic and functional description and specific MRI characteristics of the OARs. Conclusions: In the era of precision radiation therapy, the need for well-built, straightforward contouring guidelines is on the rise. Precise, uniform, delineation-based, automated OAR segmentation on MRI may lead to increased accuracy in terms of organ boundaries and analysis of dose-dependent sequelae for an adequate definition of normal tissue complication probability.