Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes
oleh: Chunyan Wang, Emma L. Hesketh, Tatiana M. Shamorkina, Wentao Li, Peter J. Franken, Dubravka Drabek, Rien van Haperen, Sarah Townend, Frank J. M. van Kuppeveld, Frank Grosveld, Neil A. Ranson, Joost Snijder, Raoul J. de Groot, Daniel L. Hurdiss, Berend-Jan Bosch
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2022-05-01 |
Deskripsi
Human coronavirus OC43 causes respiratory disease and is maintained in the human population through recurring infections. Here, by extensive structural analyses, the authors provide insights into the binding sites and breadth of neutralizing antibodies against this endemic coronavirus.