Gemcitabine in Bone Sarcoma Resistant to Doxorubicin-Based Chemotherapy

oleh: Ofer Merimsky, Isaac Meller, Yehuda Kollender, Josephine Issakov, Gideon Flusser, Moshe Inbar

Format: Article
Diterbitkan: Wiley 2000-01-01

Deskripsi

Subjects and Methods: Seven patients with progressive localized or metastatic chemo-resistant osteosarcoma were treated by gemcitabine.The protocol included gemcitabine 1000 mg/m2/w for 7 consecutive weeks, followed by 1 week rest. If no progression was observed,maintenance by gemcitabine 1000 mg/m2/w for 3 weeks every 28 days was given until failure was clinically or radiologically evident.