NK cells beat T cells at early breast cancer control
oleh: Aitziber Buque, Norma Bloy, Giulia Petroni, Guido Kroemer, Lorenzo Galluzzi
| Format: | Article |
|---|---|
| Diterbitkan: | Taylor & Francis Group 2020-01-01 |
Deskripsi
Cancer immunosurveillance generally relies on adaptive immune programs executed by CD8+ T cells. Our findings demonstrate that CD8+ T cells fail to control early oncogenesis in a mouse model of luminal B breast cancer and suggest that natural killer (NK) cells may instead play a predominant role in this setting.