The calcium channel subunit α2δ-3 organizes synapses via an activity-dependent and autocrine BMP signaling pathway
gan: Kendall M. Hoover, Scott J. Gratz, Nova Qi, Kelsey A. Herrmann, Yizhou Liu, Jahci J. Perry-Richardson, Pamela J. Vanderzalm, Kate M. O’Connor-Giles, Heather T. Broihier
| Fformat: | Article |
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| Cyhoeddwyd: | Nature Portfolio 2019-12-01 |
Disgrifiad
Activity-dependent pathways are important for synapse function but the molecular links to synapse function are not clear. The authors show that the Ca2 + channel subunit α2δ-3 provides an extracellular scaffold for autocrine BMP signalling at the Drosophila neuromuscular junction.