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Introduction: Ewing sarcoma is the second most common primary bone malignancy in adolescents. Advancement in field of imaging, revolution in reconstruction techniques, have made management of Ewings sarcoma a near success with least recurrence and better function outcomes in post operative period. Methods: This case report presents Ewings Sarcoma of left proximal humerus, managed with wide excision and reconstruction by vascularized fibular autograft with tibial Allograft with emphasizes on the technique of reconstruction. Discussion: Wide excision and reconstruction by vascularized fibular autograft with tibialautografta feasible option in the management of Ewings Sarcoma of proximal humerus with good functional outcomes and no local recurrence. Conclusion: The choice of the most appropriate surgical treatment should be considered based on resection extent as well patient’ systemic and local clinical picture, life expectancy, and functional requests. Biologic reconstructions are indicated mainly for young patients. In fact, the osteo integration and mechanic performances promised by grafts could lead to great functional results through the long life of the implant.