Pathogen-derived extracellular vesicles mediate virulence in the fatal human pathogen Cryptococcus gattii
oleh: Ewa Bielska, Marta Arch Sisquella, Maha Aldeieg, Charlotte Birch, Eloise J. O’Donoghue, Robin C. May
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-04-01 |
Deskripsi
Highly virulent cells of the fungal pathogen Cryptococcus gattiigrow rapidly within phagocytes by stimulating the growth of neighbouring fungal cells. Here, Bielska et al. show that this effect is mediated by the release of fungal extracellular vesicles that can be taken up by infected macrophages.