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Case Description- An Arabian 10-mounth-old filly with a large mass on the left lateral side of the neck was referred to the Department of Surgery, Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Shahid Bahnoar University of Kerman. Clinical Findings- In clinical examination a large, ulcerated mass (12×10×4cm diameter) was detected on left lateral side of the neck, covered with some serosangeneous discharge. Vital parameters (heart rate, respiratory rate, body temperature) were within normal range. Treatment and Outcome-The surgery was performed under general inhalation anesthesia and the mass was removed <em>en bloc</em>. Histopathological examination of the mass showed a large number of eosinophils infiltrated within the dermis and superficial hypodermis, which was diagnosed as eosinophilic granuloma. Clinical Relevance- This benign tumor is relatively common in horse which is caused mostly due to hypersensitivity reaction to some unknown allergens and chemicals and most of the times are idiopathic. The size of the tumor in this case was much larger than what is reported in the literature.