Deciphering highly similar multigene family transcripts from Iso-Seq data with IsoCon

oleh: Kristoffer Sahlin, Marta Tomaszkiewicz, Kateryna D. Makova, Paul Medvedev

Format: Article
Diterbitkan: Nature Portfolio 2018-11-01

Deskripsi

Transcripts from highly-similar multigene families are challenging to decipher. Here, the authors develop IsoCon, a tool for detecting and reconstructing isoforms from multigene families by analyzing long PacBio Iso-Seq reads.