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Interpretation of T cell states from single-cell transcriptomics data using reference atlases
oleh: Massimo Andreatta, Jesus Corria-Osorio, Sören Müller, Rafael Cubas, George Coukos, Santiago J. Carmona
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-05-01 |
Deskripsi
One challenge of single cell RNA sequencing analysis is how to consistently identify cell subtypes and states across different datasets. Here the authors propose the use of a reference single-cell atlas as a stable system of coordinates to characterize T cell states across studies, diseases and species.