Distinct populations of cortical pyramidal neurons mediate drug reward and aversion

oleh: A. F. Garcia, E. A. Crummy, I. G. Webb, M. N. Nooney, S. M. Ferguson

Format: Article
Diterbitkan: Nature Portfolio 2021-01-01

Deskripsi

The anterior cingulate plays a role in addiction, but studies have not examined the role of its two types of glutamatergic projection neurons, pyramidal tract (PT) and intratelencephalic (IT). Here we demonstrate that these two populations regulate distinct features of a drug experience, its positive and negative aspects, respectively.