Patients with COVID-19 and neurological manifestations show undetectable SARS-CoV-2 RNA levels in the cerebrospinal fluid
oleh: Otávio de Melo Espíndola, Marilda Siqueira, Cristiane Nascimento Soares, Marco Antonio Sales Dantas de Lima, Ana Claudia Celestino Bezerra Leite, Abelardo Queiroz Campos Araujo, Carlos Otávio Brandão, Marcus Tulius Teixeira Silva
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2020-07-01 |
Deskripsi
We report that patients with COVID-19 displaying distinct neurological disorders have undetectable or extremely low levels of SARS-CoV-2 RNA in the cerebrospinal fluid, indicating that viral clearance precede the neurological involvement. This finding points to the need for the development of more sensitive molecular tests and the investigation of other neurotropic pathogens to exclude concurrent neuroinfection.