AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions

oleh: Jake F. Watson, Alexandra Pinggera, Hinze Ho, Ingo H. Greger

Format: Article
Diterbitkan: Nature Portfolio 2021-08-01

Deskripsi

Changes in AMPAR localization can control the strength of synaptic transmission. Here, the authors show that the interactions of TARP γ8 and the AMPAR N-terminal domain work together to regulate receptor accumulation and positioning at the post-synapse of mouse hippocampal CA1 neurons.