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Acromegaly is a rare chronic, progressive endocrine disorder usually due to a growth hormone (GH)-secreting pituitary adenoma and characterized by progressive anatomical disfigurement, mainly involving face and extremities, and metabolic dysfunctions determined by increased circulating GH and insulin-like growth factor 1 (IGF-1) levels (1,2). A 43-year-old man photographed in 1946 by Irving Penn was the professional wrestler Maurice Tillet (1903-1954), known by the nickname “the French Angel” who inspired the Shrek animated design.