NK cells are activated and primed for skin-homing during acute dengue virus infection in humans
oleh: Christine L. Zimmer, Martin Cornillet, Carles Solà-Riera, Ka-Wai Cheung, Martin A. Ivarsson, Mei Qiu Lim, Nicole Marquardt, Yee-Sin Leo, David Chien Lye, Jonas Klingström, Paul A. MacAry, Hans-Gustaf Ljunggren, Laura Rivino, Niklas K. Björkström
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-08-01 |
Deskripsi
Here, Zimmer et al. analyze the natural killer (NK) cell response in a patient cohort with acute dengue virus infection showing early NK cell activation and proliferation, and the data suggest that NK cell proliferation depends on IL-18 signaling, and that responding NK cells have a skin-homing phenotype.