Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide
oleh: Lin-Ping Wu, Davoud Ahmadvand, Junan Su, Arnaldur Hall, Xiaolong Tan, Z. Shadi Farhangrazi, S. Moein Moghimi
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-10-01 |
Deskripsi
Bacteriophages can bind targets with only a few copies of a display peptide while most nanoparticles with thousands achieve poor binding. Here the authors form hierarchical arrangements of phage peptides to delivery siRNA across the blood brain barrier.