Find in Library

Metabolic syndrome is characterized by an increase in oxidative stress and chronic<br />low-grade inflammation. The effects of an exercise test at 60&#8211;70% of the maximum capacity was<br />evaluated on inflammatory and antioxidant response in elderly people suffering from metabolic<br />syndrome. Exercise induced significant increases in plasma levels of inflammatory cytokines and<br />malondialdehyde. The expression of these cytokines and antioxidant enzymes were also increased<br />in peripheral blood mononuclear cells. In addition, plasma levels of tumour necrosis factor alpha<br />were unchanged. In conclusion, the exercise test induces a situation of oxidative stress that<br />promotes the activation of a proinflammatory cytokine cascade.