Fatal Measles Inclusion-Body Encephalitis in Adult with Untreated AIDS, France

oleh: Christophe Rodriguez, Meriadeg Ar Gouilh, Nicolas Weiss, Sébastian Stroer, Karima Mokhtari, Danielle Seilhean, Bertrand Mathon, Vanessa Demontant, Melissa N’Debi, Guillaume Gricourt, Paul-Louis Woerther, Jean-Michel Pawlotsky, Karl Stefic, Julien Marlet, Pierre-François Dequin, Antoine Guillon, Valérie Pourcher, David Boutolleau, Astrid Vabret, Sonia Burrel

Format: Article
Diterbitkan: Centers for Disease Control and Prevention 2020-09-01

Deskripsi

We report a fatal case of measles inclusion-body encephalitis occurring in a woman from Romania with AIDS. After an extensive but unsuccessful diagnostic evaluation, a pan-pathogen shotgun metagenomic approach revealed a measles virus infection. We identified no mutations previously associated with neurovirulence.