Find in Library
Search millions of books, articles, and more
Indexed Open Access Databases
Constraint Release for Reptating Filaments in Semiflexible Networks Depends on Background Fluctuations
oleh: Tina Händler, Cary Tutmarc, Jessica S. Freitag, David M. Smith, Jörg Schnauß
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2022-02-01 |
Deskripsi
Entangled semiflexible polymer networks are usually described by the tube model, although this concept has not been able to explain all experimental observations. One of its major shortcomings is neglecting the thermal fluctuations of the polymers surrounding the examined test filament, such that disentanglement effects are not captured. In this study, we present experimental evidence that correlated constraint release which has been predicted theoretically occurs in entangled, but not in crosslinked semiflexible polymer networks. By tracking single semiflexible DNA nanotubes embedded both in entangled and crosslinked F-actin networks, we observed different reptation dynamics in both systems, emphasizing the need for a revision of the classical tube theory for entangled polymer solutions.