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With many advantages such as safety, effective cutting of enamel and dentin, Er, Cr: YSGG laser has gained more and more attention in recent years. After irradiation, the morphology, composition, and structure of tooth surface has changed, yet, the effect of these alterations to the bonding strength of the subsequent material is controver⁃ sial. The paper has made a review from the following four aspects: Mechanism for tooth hard tissue cutting with Er, Cr: YSGG laser; The structure characteristics of primary teeth; The enamel bonding strength of primary teeth after Er, Cr: YSGG laser treatment; Safety, superiority and expectation for the application of Er, Cr: YSGG laser in primary teeth.