Pseudotyped Bat Coronavirus RaTG13 is efficiently neutralised by convalescent sera from SARS-CoV-2 infected patients

oleh: Diego Cantoni, Martin Mayora-Neto, Nazia Thakur, Ahmed M. E. Elrefaey, Joseph Newman, Sneha Vishwanath, Angalee Nadesalingam, Andrew Chan, Peter Smith, Javier Castillo-Olivares, Helen Baxendale, Bryan Charleston, Jonathan Heeney, Dalan Bailey, Nigel Temperton

Format: Article
Diterbitkan: Nature Portfolio 2022-05-01

Deskripsi

Bat Coronavirus RaTG13, a sarbecovirus related to SARS-CoV-2, is more potently neutralized by antibodies from convalescent SARS-CoV-2-infected patients as well as vaccinated healthcare workers despite the spike proteins having high diversity within their receptor binding domains (RBD).