Circular RNA circTmem241 drives group III innate lymphoid cell differentiation via initiation of Elk3 transcription

oleh: Nian Liu, Jiacheng He, Dongdong Fan, Yang Gu, Jianyi Wang, Huimu Li, Xiaoxiao Zhu, Ying Du, Yong Tian, Benyu Liu, Zusen Fan

Format: Article
Diterbitkan: Nature Portfolio 2022-08-01

Deskripsi

Innate lymphoid cells (ILC) have been shown to be involved in a range of inflammatory contexts but how their cellular lineage is regulated is not fully established. Here the authors show a role for circular RNA circTmem241 in the differentiation of ILC3 via initiation of Elk3 transcription.