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We review and introduce several approaches to the study of centralizer algebras of the infinite symmetric group $S_{\infty}$. Our work is led by the double commutant relationship between finite symmetric groups and partition algebras; in the case of $S_{\infty}$, we obtain centralizer algebras that are contained in partition algebras. In view of the theory of symmetric functions in non-commuting variables, we consider representations of $S_{\infty}$ that are faithful and that contain invariant elements; namely, non-unitary representations on sequence spaces.